health care products

Appetite suppressant

Obesity is the major health risk for the development of several diseases including cardiovascular problems, arthritis, high blood pressure and diabetes. There are many ways to control weight and thus treat obesity, for example, diet, medications, physical activity, surgery, jaw wiring, behavior modification, and self-help organizations. Appetite is one important regulatory pathway that can be targeted to treat obesity and obesity-related disorders. There are many appetite suppressant products on the market, both prescription items and over the counter products. Most of these products act as central nervous system stimulants, such as amphetamines, or have a similar mechanism of action. Examples of known appetite reducing agents are ephedrine which is an extract of the herb Ma huang (Ephreda sinica), phenylpropanolamine (PPA), amphetamines and fenfluramine alone or in combination with caffeine. Caffeine functions probably to reduce fatigue as caffeine has stimulating properties. Phenylpropanolamine (PPA) is a popular over-the-counter drug for appetite suppression and its side effects are well documented. Dopamine is believed to be involved in the neuropathways responsible for appetite-suppression. Dopamine itself is not used as an appetite-suppressant because it does not readily cross the blood brain barrier. Drugs which closely resemble the structure of dopamine and which will cross the blood brain barrier have been used with some success as alternatives to dopamine. Dopamine is also known to play a crucial role in several neurologically related disorders. For example, Parkinsonism is a striatal dopamine deficiency. Because dopamine does not cross the blood brain barrier Parkinsonism is treated with L-dopa, a precursor to dopamine. A widely used appetite-suppressant drugs are generally based on derivatives of amphetamine, which structurally resembles dopamine and has some properties which correspond to a dopamine agonist. Unlike dopamine, sufficient uptake of amphetamines across the blood brain barrier does occur to produce a biological effect. However, amphetamines have many serious cardiovascular and neuropsychiatric side effects, as well as a tendency to develop tolerance, the increasing resistance to the usual effect of the drug over time.

productsRecommended appetite suppressant products








Category Jump :