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Guggul

Guggul extract is extracted from the plants of the genis commiphora, particularly Commiphora mukul or Commiphora wightii or the chemically synthesized active components thereof. The guggul extract is obtained from the gum/resin of these plants, shrubs, or trees and is a complex mixture of terpenes, sterols, esters, and higher alcohols. The ethylacetate extract of the resin is an oily material also known as "gugulipid" or "guggal lipid". The pharmacological activity of gugulipid is attributed to two known ketonic steroids. The guggul extract contains from 5-50% by weight of the guggulsterones, more preferably at least 10% by weight. It is known that the plant Commiphora mukul belongs to the family of the Burseraceae. Commiphora mukul has long been used as a herbal treatment for hyperlipidaemia in the form of a gum resin called "guggulipid" or "guggal lipid". Commiphora mukul is a plant of Indian origin which is very widely used in traditional Indian medicine and in ayurvedic medicine. A resin produced by Commiphora mukul, which is also called guggul, is used in particular in these applications. This ayurvedic treatment was known to comprise the treatment of obesity and lipidic disorders, as well as rheumatic diseases.

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